| 发明名称 |
|
| 摘要 |
A mutant strain having an ability to produce L-glutamic acid in the absence of any biotin action-suppressing agent in a medium containing an excessive amount of biotin is obtained by giving temperature sensitivity to a biotin action-suppressing agent to a coryneform L-glutamic acid-producing bacterium. This strain is cultivated in a liquid medium to produce and accumulate L-glutamic acid in the medium. A mutant strain having an ability to produce L-lysine and L-glutamic acid in the absence of any biotin action-suppressing agent in a medium containing an excessive amount of biotin is obtained by giving temperature sensitivity to a biotin action-suppressing agent and L-lysine productivity to a coryneform L-glutamic acid-producing bacterium. This strain is cultivated in a liquid medium to simultaneously produce and accumulate L-lysine and L-glutamic acid in the medium. |
| 申请公布号 |
JP2926991(B2) |
申请公布日期 |
1999.07.28 |
| 申请号 |
JP19960507633 |
申请日期 |
1995.08.09 |
| 申请人 |
AJINOMOTO KK |
发明人 |
KIMURA EIICHIRO;ASAKURA YOKO;UEHARA AKYOSHI;INOE SUMIO;KAWAHARA YOSHIO;YOSHIHARA YASUHIKO;NAKAMATSU WATARU |
| 分类号 |
C12N1/21;C12N15/09;C12P13/08;C12P13/14;(IPC1-7):C12P13/08 |
主分类号 |
C12N1/21 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
