Amidine and isothiourea derivatives, compositions containing them and their use as inhibitors of nitric oxide synthase

摘要

PCT No. PCT/SE96/01425 Sec. 371 Date Jan. 22, 1997 Sec. 102(e) Date Jan. 22, 1997 PCT Filed Nov. 6, 1996 PCT Pub. No. WO97/17344 PCT Pub. Date May 15, 1997There are provided novel compounds of formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined in the specification and optical isomers and racemates thereof and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy.