发明名称 |
DIFFUSION-OSMOSIS PHARMACEUTICAL SYSTEM WITH CONTROLLED DRUG RELEASE (VERSIONS) AND METHOD OF PREPARATION THEREOF |
摘要 |
FIELD: pharmaceutical products. SUBSTANCE: system contains single-layer pellet core and polymer film coating. Core includes therapeutically active agent and hydrophilic polymer. In another version of invention, double-layer pellet core contains active substance and hydrophilic polymer in its first layer and hydrophilic polymer in its second layer. System has at least one opening in a part of film coating which is in contact with core or active substance-containing core layer. System may also have one ore several openings in its part being in contact with the second layer. Coating consists of ammonium-methacrylate copolymer and hydrophilic polymer is hydroxypropylmethylcellulose. EFFECT: eliminated use chlorinated solvents. 34 cl, 9 dwg, 2 tbl, 6 ex
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申请公布号 |
RU2133605(C1) |
申请公布日期 |
1999.07.27 |
申请号 |
RU19940043798 |
申请日期 |
1994.12.09 |
申请人 |
EHGISH D'OD'SERD'AR RT. |
发明人 |
PAL FEKESHE;MARIJA KIRALI;GABOR SHIPOSH;SJUZANNA JAMBOR;D'ORD' JUZHFALUSSI;MAGDOLNA GORA;IMRE KLEBOVICH;SHANDOR DRABANT;ATTILA MANDI;GIZELA KISS;EHRSEBET BARCHAI;MARIJA KRISTIAN |
分类号 |
A61K9/36;A61J3/10;A61K9/00;A61K9/22;A61K9/32;A61K47/34;(IPC1-7):A61K9/22 |
主分类号 |
A61K9/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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