发明名称 Bifunctional acetylcholinesterase reactivators
摘要 Compounds of formula I:Ar1 -R1-Ar2(I)wherein Ar1, Ar2, and R1 have any of the values defined in the specification, and their pharmaceutically acceptable salts, are acetylcholinesterase (AChE) reactivators useful as antidotes for organophosphate poisoning in mammals. Also disclosed are pharmaceutical compositions, processes for preparing compounds of formula (I), methods for the use of compounds of formula (I), and intermediates for the preparation thereof.
申请公布号 US5929093(A) 申请公布日期 1999.07.27
申请号 US19970873794 申请日期 1997.06.12
申请人 MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH 发明人 PANG, YUAN-PING;BRIMIJOIN, STEPHEN
分类号 C07D213/53;(IPC1-7):A01N43/40;C07D401/00 主分类号 C07D213/53
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