| 摘要 |
PROBLEM TO BE SOLVED: To enable an RNA useful as a raw material of a medicine or a seasoning to be generated and accumulated in a fungal body at a high content by aerobically culturing Candida utilis mutant imparted with a highly low temperature sensitivity. SOLUTION: This mutant, e.g. Candida utilis 27B4317 (FREM P-16552), extremely reduced in the propagation rate at a low temperature and generating and accumulating an RNA in an amount of >=20 wt.% per the fungal body weight is obtained by subjecting Candida utilis CS 7529 (FREM P-3340), etc., to a mutation treatment. The mutant is aerobically cultured and the RNA is industrially obtained in an excellent productivity. |
