发明名称 |
G protein-related kinase mutants in essential hypertension |
摘要 |
The present invention provides diagnostic tests in which to identify individuals predisposed to essential hypertension, and the genetic, cellular and biochemical tools in which to carry out these tests. The present invention also provides methods of screening substances for antihypertensive properties in which to facilitate drug discovery for antihypertensive agents. A wide variety of tools are provided for these purposes as well. The present invention further provides compositions and methods for normalizing sodium transport in kidney cells of individuals having essential hypertension. |
申请公布号 |
AU2223899(A) |
申请公布日期 |
1999.07.26 |
申请号 |
AU19990022238 |
申请日期 |
1999.01.12 |
申请人 |
GEORGETOWN UNIVERSITY MEDICAL CENTER;UNIVERSITY OF VIRGINIA PATENT FOUNDATION |
发明人 |
ROBIN FELDER;PEDRO JOSE |
分类号 |
A01K67/027;A61P9/12;C07K14/72;C12N5/10;C12N15/09;C12Q1/48;C12Q1/68 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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