| 摘要 |
Described herein are compounds having general formula (I), wherein: Ar represents an aryl group optionally substituted with substituents selected from the group consisting of lower alkyl, lower alkoxy, halo, NO2, Ph, CF3, CN, OH, SO2NRR', NRR' and CO2R, where R and R' are independently selected from the group consisting of H and lower alkyl; Ar<1> and Ar<2> are independently selected Ar groups; R<3> is selected from the group consisting of H and Ar; R<4>, R<5>, R<6> and R<7> are independently selected from the group consisting of H and lower alkyl; R<8> is selected from the group consisting of H and an alkyl group having up to 8 carbon atoms, X is selected from the group consisting of S, SO, SO2, NR and CRR', where R and R' are independently selected from the group consisting of H and lower alkyl; and stereoisomers, salts, solvates or hydrates thereof. Also described is the use of these compounds as pharmaceuticals. |
