发明名称 CHELATING AGENTS
摘要 The invention provides a complexant compound of formula (I): R<3>S(CR<1>2)nN(R<2>)i(CR<1>2)nX(CR<1>2)nN(R<2>)i(CR<1>2)nSR<3>, (wherein each n, which may be the same or different, is an integer 2, 3 or 4 (preferably 2); each i, which may be the same or different, represents 0 or 1; each R<3>, which may be the same or different, is H or a thiol protecting group, preferably a protecting group; X is O, S, N, NR<4> or a substituted phosphorus (e.g. oxo substituted phosphorus), preferably S or N; each R<4>, which may be the same or different, is hydrogen or an optionally substituted organic group; each R<2>, which may be the same or different, is hydrogen or an optionally substituted organic group; each R<1>, which may be the same or different, is hydrogen or an optionally substituted organic group, or a moiety CR<1>2 may represent a carbonyl group or two, three or four R<1>S on two different carbons together with those carbons and any intervening atoms may represent an optionally substituted saturated or unsaturated homocyclic or heterocyclic ring; and preferably, at least one CR<1>2 moiety is other than CH2 or CH(CH3)) or a salt or complex thereof, wherein optionally at least one of the R<1>, R<2>, R<3> and R<4> moieties is coupled directly or indirectly to a vector moiety.
申请公布号 WO9846276(A8) 申请公布日期 1999.07.22
申请号 WO1998GB01078 申请日期 1998.04.14
申请人 NYCOMED IMAGING AS;GOLDING, LOUISE;YU, SHI-BAO;SINGH, JASBIR 发明人 YU, SHI-BAO;SINGH, JASBIR
分类号 C07D233/14;A61K49/00;A61K49/04;A61K49/08;A61K51/00;A61K51/04;A61P35/00;C07C323/59;C07C323/60;C07D213/52;C07D213/53;C09K3/00;(IPC1-7):A61K51/04 主分类号 C07D233/14
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