发明名称 |
RIBOZYMES TARGETED TO IL-15 mRNA |
摘要 |
Enzymatic RNA molecules which cleave mRNA encoding IL-15, are provided. The constructs of the invention include regulatory regions for expression in cells, cell lines, or transgenic non-human animals. The ribozymes of the invention are directed against IL-15 mRNA and are useful in treating rheumatoid arthritis. |
申请公布号 |
WO9923208(A3) |
申请公布日期 |
1999.07.22 |
申请号 |
WO1998IB01837 |
申请日期 |
1998.10.29 |
申请人 |
HISAMITSU PHARMACEUTICAL CO., INC. |
发明人 |
VEERAPANENI, DANGE;HAMANAKA, SHAII;NOZAWA, IWAO |
分类号 |
A01K67/027;A61K31/7105;A61K38/00;A61P19/02;A61P29/00;C12N5/10;C12N9/12;C12N15/09;C12N15/113 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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