发明名称 RIBOZYMES TARGETED TO IL-15 mRNA
摘要 Enzymatic RNA molecules which cleave mRNA encoding IL-15, are provided. The constructs of the invention include regulatory regions for expression in cells, cell lines, or transgenic non-human animals. The ribozymes of the invention are directed against IL-15 mRNA and are useful in treating rheumatoid arthritis.
申请公布号 WO9923208(A3) 申请公布日期 1999.07.22
申请号 WO1998IB01837 申请日期 1998.10.29
申请人 HISAMITSU PHARMACEUTICAL CO., INC. 发明人 VEERAPANENI, DANGE;HAMANAKA, SHAII;NOZAWA, IWAO
分类号 A01K67/027;A61K31/7105;A61K38/00;A61P19/02;A61P29/00;C12N5/10;C12N9/12;C12N15/09;C12N15/113 主分类号 A01K67/027
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