| 发明名称 |
IMMUNOSTIMULATORY OLIGONUCLEOTIDES, COMPOSITIONS THEREOF AND METHODS OF USE THEREOF |
| 摘要 |
The invention relates to immunostimulatory oligonucleotide compositions. These oligonucleotides comprise an immunostimulatory octanucleotide sequence. These oligonucleotides can be administered in conjunction with an immunostimulatory peptide or antigen. Methods for modulating an immune response upon administration of the oligonucleotide are also disclosed. In addition, an in vitro screening method to identify oligonucleotides with immunostimulatory activity is provided.
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| 申请公布号 |
WO9855495(B1) |
申请公布日期 |
1999.07.22 |
| 申请号 |
WO1998US11578 |
申请日期 |
1998.06.05 |
| 申请人 |
DYNAVAX TECHNOLOGIES CORPORATION;SCHWARTZ, DAVID;ROMAN, MARK;DINA, DINO |
发明人 |
SCHWARTZ, DAVID;ROMAN, MARK;DINA, DINO |
| 分类号 |
C12N15/09;A61K31/7052;A61K31/7088;A61K31/7115;A61K38/00;A61K39/39;A61K48/00;A61P37/02;A61P37/06;A61P43/00;C07H21/00;C07K14/00;C07K14/47;C12N15/117;C12Q1/68;(IPC1-7):C07H21/00;A61K31/70 |
主分类号 |
C12N15/09 |
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