Use of polymers as cell growth substrates

摘要

PCT No. PCT/EP96/01340 Sec. 371 Date Jan. 6, 1998 Sec. 102(e) Date Jan. 6, 1998 PCT Filed Mar. 27, 1996 PCT Pub. No. WO96/31548 PCT Pub. Date Oct. 10, 1996Cell growth substrate polymers are described which comprise a macromonomer of the formula (I): Q-(PFPE-L)n-1-PFPE-Q, wherein n is at least 1.0; each PFPE may be the same or different and is a perfluorinated polyether of the formula (II): -OCH2CF2O (CF2CF2O)x(CF2O)y CF2CH2O-, wherein the CF2CF2O and CF2O units may be randomly distributed or distributed as blocks throughout the chain and wherein x and y may be the same or different such that the molecular weight of the perfluoropolyether is in the range of from 242 to 4000, L is a difunctional linking group; and Q at each end of the macromonomer is the same or different and is a polymerizable group. The cell growth substrate polymers may be used in the production of comeal implants.