发明名称 |
METHODS AND COMPOSITIONS FOR GENE DELIVERY |
摘要 |
Methods and compositions are described for the efficient delivery and expression of recombinant polynucleotides in animal cells in vitro or in vivo. In particular, a comprehensive approach of non-viral gene delivery is provided that has been optimized with regards to the vectors delivered, maximizing the amount and duration of gene expression, and methods of conditioning the patient to enhance the efficiency of gene delivery. The described methods find application in both gene therapy, and the functional analysis of cloned gene products in vivo.
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申请公布号 |
CA2318663(A1) |
申请公布日期 |
1999.07.22 |
申请号 |
CA19992318663 |
申请日期 |
1999.01.15 |
申请人 |
CALIFORNIA PACIFIC MEDICAL CENTER RESEARCH INSTITUTE |
发明人 |
DEBS, ROBERT J. |
分类号 |
A01K67/027;A61K31/573;A61K31/711;A61K31/716;A61K38/00;A61K38/17;A61K38/19;A61K38/22;A61K38/43;A61K47/28;A61K47/36;A61K47/48;A61K48/00;A61P35/00;C07K14/05;C07K14/52;C07K14/535;C12N15/09;C12N15/85;C12N15/87;C12N15/88;(IPC1-7):C12N15/09 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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