| 摘要 |
<p>Compounds represented by general formula (I), pharmaceutically acceptable salts thereof, or hydrates of both; and endothelin B receptor selective antagonists containing the same. In said formula4R?1 and R2¿ are each independently optionally substituted aryl; R3 is hydrogen or the like; X is O, S or the like; Y is lower alkylene or the like; Z is CONR?4R5, CH=CR6R7¿ or CH=NNR?8R9; R4 and R5¿ are each independently hydrogen, lower alkyl or the like; R?6 and R7¿ are each independently acyl, lower alkoxycarbonyl or the like; and R?8 and R9¿ are each hydrogen, acyl or the like.</p> |
