发明名称 |
Adhesion receptor blocker for ÓV-integrins. |
摘要 |
The invention relates to a novel monoclonal antibody and a hybridoma cell line producing said antibody. The monoclonal antibody, a preferred embodiment of which is named 14D9.F8, has the following properties: reacting only with the alpha v-chain of human alpha v-integrins, and inhibiting selectively the attachment to the integrin substrate fibronectin of the alpha v beta 6-integrin bearing cell. |
申请公布号 |
ZA9900453(B) |
申请公布日期 |
1999.07.21 |
申请号 |
ZA19990000453 |
申请日期 |
1999.01.21 |
申请人 |
MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG |
发明人 |
SIMON GOODMAN;BEATE DIEFENBACH;FRANCESC MITJANS;ELISABET ROSELL-VIVES;ANA CARCELLER |
分类号 |
C12N15/09;A61K38/00;A61K39/395;A61K49/00;A61K51/00;A61P35/00;C07K16/28;C12N5/10;C12N5/20;C12P21/08 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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