| 发明名称 |
Alkylated styrenes as prodrugs to COX-2 inhibitors |
| 摘要 |
The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.
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| 申请公布号 |
US5925631(A) |
申请公布日期 |
1999.07.20 |
| 申请号 |
US19980128140 |
申请日期 |
1998.08.03 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
BLACK, CAMERON;HUGHES, GREG;GRIMM, ERICH;LEGER, SERGE;PRASIT, PETPIBOON;WANG, ZHAOYIN |
| 分类号 |
C07C311/29;C07C317/22;C07C317/24;C07C317/44;C07C317/46;C07D307/58;C07D307/60;C07D307/64;C07D307/66;C07D307/94;C07D405/12;(IPC1-7):C07D209/44;C07D213/30;C07D217/16;C07D211/22;C07D307/32;A61K31/44;A61K31/445;A61K31/47 |
主分类号 |
C07C311/29 |
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