发明名称 Process for the preparation of lamotrigine
摘要 PCT No. PCT/GB95/03049 Sec. 371 Date Jun. 25, 1997 Sec. 102(e) Date Jun. 25, 1997 PCT Filed Dec. 29, 1995 PCT Pub. No. WO96/20935 PCT Pub. Date Jul. 11, 1996Lamotrigine, 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine, may be prepared by treating 6-(2,3-dichlorophenyl)-5-chloro-3-thiomethyl-1,2,4-triazine of formula (II) with ammonia. Precursors to the compound of formula (II), and their preparation, are also described.
申请公布号 US5925755(A) 申请公布日期 1999.07.20
申请号 US19970836152 申请日期 1997.06.25
申请人 GLAXO WELLCOME INC. 发明人 LEE, GRAHAME ROY
分类号 C07D253/06;C07D253/07;C07D253/075;(IPC1-7):C07D253/075 主分类号 C07D253/06
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