| 发明名称 |
Benzofuran carboxamides and their therapeutic use |
| 摘要 |
Compounds having the formula (i), wherein the groups R1, R2, R3, R4 and R5 are defined herein. The compounds of the present invention can be utilized to treat disease states capable of being modulated by inhibition of proteins which mediate cellular activity, such as tumor necrosis factor (TNF) and/or phosphodiesterase IV (PDE IV).
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| 申请公布号 |
US5925636(A) |
申请公布日期 |
1999.07.20 |
| 申请号 |
US19970859509 |
申请日期 |
1997.05.20 |
| 申请人 |
DARWIN DISCOVERY LIMITED |
发明人 |
DYKE, HAZEL JOAN;LOWE, CHRISTOPHER;MONTANA, JOHN GARY |
| 分类号 |
C07D307/79;A61K31/00;A61K31/34;A61K31/343;A61K31/415;A61K31/4155;A61K31/435;A61K31/4353;A61K31/4375;A61K31/44;A61K31/4427;A61K31/443;A61K31/505;A61K31/506;A61K31/53;A61K31/535;A61K31/5375;A61K31/5377;A61P11/00;A61P11/06;A61P25/18;A61P25/28;A61P29/00;A61P37/00;A61P37/08;A61P43/00;C07D307/80;C07D307/81;C07D307/86;C07D405/04;C07D405/12;C07D405/14;C07D417/12;C07D417/14;C07D471/04;(IPC1-7):C07D307/83;C07D401/12 |
主分类号 |
C07D307/79 |
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