发明名称 |
Novel beta-lactamase and dd-peptidase inhibitors |
摘要 |
The invention provides novel beta-lactamase inhibitors, which are structurally unrelated to the natural product and semi-synthetic beta-lactamase inhibitors presently available, and which do not possess beta-lactam pharmacophore. These new inhibitors are fully synthetic, allowing ready access to a wide variety of structurally related analogs. Certain embodiments of these new inhibitors also bind bacterial DD-peptidases, thus potentially acting both as beta-lactamase inhibitors and as antibiotics. |
申请公布号 |
AU2094599(A) |
申请公布日期 |
1999.07.19 |
申请号 |
AU19990020945 |
申请日期 |
1998.12.23 |
申请人 |
METHYLGENE, INC.;WESLEYAN UNIVERSITY |
发明人 |
JEFFREY M. BESTERMAN;JUBRAIL RAHIL;REX PRATT |
分类号 |
A61K31/662;A61P31/04;A61P43/00;C07F9/09;C07F9/40;C07F9/6571;C07F9/6574 |
主分类号 |
A61K31/662 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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