Polyethoxylated castor oil, process of making the same and formulations thereof
摘要
Polyethoxylated castor oil with a low cation content are claimed, along with particular methods for achieving such low cation content polyethoxylated castor oil. One method of production of such a low cationic content polyethoxylated castor oil according to the invention is to pre-treat the polyethoxylated castor oil with a strong cationic exchange resin to remove a substantial portion of the cations present in an untreated polyethoxylated castor oil. The low cationic content polyethoxylated castor oil of the invention can then be utilized to prepare formulations of various agents which are found to be sensitive to the previously commercially available polyethoxylated castor oil (CREMOPHOR EL TM ).
申请公布号
US5925776(A)
申请公布日期
1999.07.20
申请号
US19970998306
申请日期
1997.12.24
申请人
SCHEIN PHARMACETICAL, INC.
发明人
NIKOLAYEV, ALEKSANDR;SAYEED, FAKRUL;IYER, RUPA;GARBER, MITCHELL;BUTTERHOF, ROBERT C.;HOYER, TODD M.;SAMSON, MARVIN