摘要 |
<p>An oncogene designated ZNF198-FGFR1 incorporates an FGFR1 tyrosine kinase domain fused through translocation to ZNF198, a zinc finger gene and is associated with stem-cell leukemia/lymphoma syndrome. Molecular characterization of ZNF198-FGFR1 and of ZNF198 provides nucleic acid sequences and amino acid sequences useful for detection and treatment of stem-cell leukemia/lymphoma syndrome.</p> |