| 发明名称 |
VACCINE WITH NON-COMPLEX HERPES VIRUS |
| 摘要 |
<p>A vaccine is described which comprises an assembly-deficient herpesvirus. The mutant herpesvirus is capable of infecting and undergoing DNA replication in the cells of a susceptible mammal, but is defective in capsid assembly and formation of mature virion particles. The assembly-deficient herpesvirus is avirulent and capable of generating a protective immune response in a vaccinated mammal.</p> |
| 申请公布号 |
CZ9900179(A3) |
申请公布日期 |
1999.07.14 |
| 申请号 |
CZ19990000179 |
申请日期 |
1997.07.25 |
| 申请人 |
G. D. SEARLE & CO. |
发明人 |
HIPPENMEYER PAUL J.;RENKIN ANNE M.;LUCKOW VERNE A. |
| 分类号 |
C12N15/09;A61K38/46;A61K39/00;A61K39/245;A61K48/00;A61P31/22;C12N5/10;C12N7/00;C12N9/50;C12N15/52;C12R1/92;(IPC1-7):A61K39/245;C12N15/38 |
主分类号 |
C12N15/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
