| 发明名称 |
USE OF CYCLOOXYGENASE-2 INHIBITORS FOR TREATING AND PREVENTION OF NEOPLASIA |
| 摘要 |
<p>This invention relates to the use of cyclooxygenase-2 inhibitors or derivatives thereof in preventing and treating neoplasia. In particular, the invention describes the method of preventing and treating epithelial cell neoplasia in a subject, said method comprising treating the subject with a therapeutically-effective amount of a compound of Formula (I) wherein A, R<2> and R<3> are as described in the specification.</p> |
| 申请公布号 |
CZ9901171(A3) |
申请公布日期 |
1999.07.14 |
| 申请号 |
CZ19990001171 |
申请日期 |
1997.10.14 |
| 申请人 |
G. D. SEARLE & CO. |
发明人 |
SEIBERT KAREN;MASFERRER JAIME;GERDON GARY B. |
| 分类号 |
C07D233/64;A61K31/10;A61K31/18;A61K31/415;A61K31/4164;A61K31/4178;A61K31/42;A61K31/421;A61K31/426;A61K31/427;A61K31/44;A61K31/4418;A61K31/4439;A61K31/635;A61K45/06;A61P35/00;A61P43/00;C07D;C07D213/85;C07D231/12;C07D261/08;C07D263/32;C07D277/20;C07D277/26;C07D277/46;C07D401/04;C07D417/04;(IPC1-7):A61K31/415 |
主分类号 |
C07D233/64 |
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