| 主权项 |
1．一种从海绵中提取的胆甾醇醋酸酯，其特征在于该化合物从南海海绵中用权利要求2中所述的方法提取分离并经化学反应获得，结构式如下：<img file="A9812222500021.GIF" wi="807" he="372" />化学名称：25(29)-亚甲基-26-甲基-26-乙基胆甾醇醋酸酯，该化合物物理常数为：m.p.102～104℃；[α]<sub>D</sub><sup>20</sup>(CH<sub>2</sub>Cl<sub>2</sub>,C=9.76mg/ml,C=0.97)-44.6°；ν<sub>max</sub><sup>KBr</sup>(cm<sup>-1</sup>):3438,2937,2823,1731,1641,1463,1371,1332,1249,1135,1039,962,887,833；δ<sup>1</sup>H(CDCl<sub>3</sub>):5.38(1H,d,J=4.5Hz,6-H),4.70(2H,S,29-H),4.61(1H,m,3α-H),2.03(3H,S,-OCH<sub>3</sub>),1.02(3H,S,19-CH<sub>3</sub>),1.00(3H,d,J=6.95Hz,30-CH<sub>3</sub>),0.95(3H,d,J=6.64Hz,21-CH<sub>3</sub>),0.84(3H,t,J=7.40,28-CH<sub>3</sub>),0.69(3H,S,18-CH<sub>3</sub>)；δ<sup>13</sup>C(CDCl<sub>3</sub>):170.53(C=O),155.28(C<sub>25</sub>),139.65(C<sub>5</sub>),122.61(C<sub>6</sub>),107.08(C<sub>29</sub>),73.99(C<sub>3</sub>),56.68(C<sub>14</sub>),55.99(C<sub>17</sub>),50.80(C<sub>10</sub>),50.05(-OCH<sub>3</sub>),42.35(C<sub>4</sub>),41.70(C<sub>13</sub>),39.74(C<sub>26</sub>),38.12(C<sub>12</sub>),36.99(C<sub>1</sub>),36.59(C<sub>20</sub>),35.76(C<sub>22</sub>),34.63(C<sub>7</sub>),31.88(C<sub>8</sub>),31.88(C<sub>9</sub>),30.39(C<sub>23</sub>),28.28(C<sub>2</sub>),28.16(C<sub>24</sub>),27.77(C<sub>27</sub>),24.26(C<sub>16</sub>),21.38(C<sub>15</sub>),21.03(C<sub>11</sub>),19.79(C<sub>19</sub>),19.28(C<sub>30</sub>),18.72(C<sub>21</sub>),11.94(C<sub>28</sub>),11.84(C<sub>18</sub>)；m/z:408(15.4),394(61.7),296(100),147(54.62),145(60.33),81(71.6),69(54.6),55(71.4),43(77.6)。 |
