| 摘要 |
PROBLEM TO BE SOLVED: To obtain in an industrially advantageous way the subject high-purity compound useful as an intermediate for manufacturing compounds having plant disease injury control efficacy by reacting a specified methylphenylacetic acid derivative with bromine in the presence of an alkali metal salt and recrystallizing the resultant reaction product in an aliphatic hydrocarbon solution. SOLUTION: This compound of formula II is obtained by reacting (A) a methylphenylacetic acid derivative of formula I (R1 is ethyl or isopropyl) [e.g. (E)-α-methoxyimino-o-tolylacetic acid ethyl ester], (B) preferably in the presence of an alkali metal salt such as carbonate (e.g. sodium carbonate) with (C) bromine preferably at rates of 1.5-5.0 mol component B and 0.9-1.2 mol component C per mol component A, preferably at 80-95 deg.C and usually for 0.5-10 h and recrystallizing the resultant reaction product preferably in (D) an aliphatic hydrocarbon solution such as n-hexane preferably using 4-6 g component D per g component A.
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