Pdzk1 protein containing pdz interaction domains

摘要

The present invention provides a unique DNA segment and a previously unknown PDZK1 protein as a marker system indicative of cells and tissues in an abnormal cellular state and which are undergoing a progressive loss of cell regulation and control. The isolated DNA sequence encodes the PDZK1 protein; and the expressed PDZK1 protein, particularly when present in large or excessive quantitative amounts, is a reliable and reproducible biochemical marker that an ongoing neoplastic development is occurring within cell and tissues of epithelial cell origin.