| 摘要 |
The antibiotic TKR2999 having the physicochemical properties described below and its pharmacologically acceptable salt: (1) FAB-MS m/z 971 ÄM+HÜ<+>, (2) the molecular formula: C44H78N10O14, and high-resolution FAB-MS m/z 971.5776 ÄM+HÜ<+>, (3) the ultraviolet absorption spectrum in methanol has an end absorption, (4) the infrared absorption spectrum by KBr method shows the major absorption wave numbers at 3320, 2920, 1680, 1540, 1210, 1140, 840, 800, and 720 cm<-1>, (5) aspartic acid, threonine, serine, glycine, alanine, beta -alanine, and ornithine are detected by the amino acid analysis using ninhydrin reaction, and (6) the solubility is that it is soluble in methanol, and practically insoluble in hexane, chloroform, and water. The novel antibiotic is useful as a therapeutic agent for fungal infection diseases. |
