发明名称 |
NOVEL POLYMERIZABLE FATTY ACIDS, PHOSPHOLIPIDS AND POLYMERIZED LIPOSOMES THEREFROM |
摘要 |
The invention relates to an oral drug delivery system which delivers biologically active substances to the mucosal tissue of the intestine utlizing novel polymerized liposomes. Novel polymerizable fatty acids having a polymerizable group, a surfactant group, and a functional group, and optionally coupled to ligands which target mucosal tissue in the intestine are disclosed. Novel negatively charged polymerizable lipids which have phosphatidyl inositol (PI), phosphatidyl glycerol (PG) or phosphatidyl serine (PS) groups on a polymerizable backbone are also described.
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申请公布号 |
WO9933940(A1) |
申请公布日期 |
1999.07.08 |
申请号 |
WO1998US27683 |
申请日期 |
1998.12.28 |
申请人 |
ORASOMAL TECHNOLOGIES, INC. |
发明人 |
BREY, ROBERT, N.;LIANG, LIKAN |
分类号 |
A61K9/127;A61K39/00;C07C69/587;C07F9/10;C08G65/329;C11C3/00;(IPC1-7):C11C3/00;C11C3/06;C08G63/47 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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