EXPRESSION AND REFOLDING OF TRUNCATED RECOMBINANT MAJOR OUTER MEMBRANE PROTEIN ANTIGEN (r56) OF ORIENTIA TSUTSUGAMUSHI AND ITS USE IN ANTIBODY BASED DETECTION ASSAYS AND VACCINES

摘要

A recombinant, refolded non-fusion polypeptide expressed from a truncated r56 gene of the causative agent of scrub typhus, Orientia tsutsugamushi. The invention is useful for detecting prior exposure to scrub typhus and as a component in vaccine formulations.