发明名称 HYPERHYDRATED CITICOLINE, PROCESS AND USE
摘要 A hyperhydrated form of citicoline and its formulations, which exhibits desirable characteristics, including crystal formation, moisture resistance, improved storage stability, and formulation versatility, is disclosed. Methods of preparing the citicoline hyperhydrate and its use in the manufacture of stable pharmaceutical dosage forms are also described.
申请公布号 WO9933476(A1) 申请公布日期 1999.07.08
申请号 WO1998US27435 申请日期 1998.12.23
申请人 INTERNEURON PHARMACEUTICALS, INC. 发明人 LERCH, GREGORY, H.
分类号 C07H19/10;A01N43/04;A61K9/20;A61K9/48;A61K31/7042;A61K31/7052;A61K31/7064;A61K31/7068;A61P9/00;A61P9/10;A61P25/00;(IPC1-7):A61K31/70 主分类号 C07H19/10
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