| 摘要 |
A process for producing an antibody catalyst capable of cleaving and/or decomposing a target protein or peptide. This process comprises constructing a monoclonal antibody by using as an antigen the target protein or peptide or a peptide fragment constituting the same, and then recovering from the thus constructed monoclonal antibody the antibody catalyst capable of cleaving and/or decomposing the target protein or peptide. To recover the antibody catalyst, it is preferable to separate the monoclonal antibody into its light chain and heavy chain. For example, the light chain of a monoclonal antibody constructed by using a peptide YP41-1 present on the constant region of an HIV surface protein gp41 has a capability of cleaving the peptide YP41-1 and the protein gp41.
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