发明名称 |
GENE EXPRESSION PROFILES IN NORMAL AND CANCER CELLS |
摘要 |
As a step towards understanding the complex differences between normal and cancer cells, gene expression patterns were examined in gastrointestinal tumors. More than 300,000 transcripts derived from at least 45,000 different genes were analyzed. Although extensive similarity was noted between the expression profiles, more than 500 transcripts that were expressed at significantly different levels in normal and neoplastic cells were identified. These data provide insights into the extent of expression differences underlying malignancy and reveal genes that are useful as diagnostic or prognostic markers. |
申请公布号 |
WO9853319(A3) |
申请公布日期 |
1999.07.08 |
申请号 |
WO1998US10277 |
申请日期 |
1998.05.20 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY;VOGELSTEIN, BERT;KINZLER, KENNETH, W. |
发明人 |
VOGELSTEIN, BERT;KINZLER, KENNETH, W. |
分类号 |
C12Q1/68;G01N33/574 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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