发明名称 VERFAHREN ZUR HERSTELLUNG VON ERGOLIN DERIVATEN
摘要 The invention provides a process for the preparation of ergoline derivatives of the formula I <IMAGE> I the process comprising reacting an ergoline amide of the formula II with an isocyanate of formula III <IMAGE> in presence of a metal catalyst and of a phosphorus compound. The compounds of the formula I are useful antiprolactinic and antiparkinson agents.
申请公布号 DE69325138(D1) 申请公布日期 1999.07.08
申请号 DE1993625138 申请日期 1993.02.15
申请人 PHARMACIA & UPJOHN S.P.A., MAILAND/MILANO, IT 发明人 CANDIANI, ILARIA, I-21052 BUSTO ARSIZIO, IT;CABRI, WALTER, I-20089 ROZZANO, IT;BEDESCHI, ANGELO, I-20146 MILAN, IT;ZARINI, FRANCO, I-20019 SETTIMO MILANESE, IT
分类号 A61K31/48;A61P5/08;A61P25/16;C07D457/06 主分类号 A61K31/48
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