Estimation of change in bone mineral density and diagnosis of osteoporosis

摘要

A method for estimation of the change in bone mineral density or a method for diagnosis of osteoporosis, comprising the step of measuring the change in the concentration of the soluble interleukin-6 receptor in a blood sample, by for example, a sandwich assay or a competition assay; and a kit for carrying out said methods, comprising: (1) an anti-sIL-6R antibody immobilized to a solid carrier, and (2) an anti-sIL-6R antibody bound to a detectable marker or capable of binding to a detectable marker.