Derivatization of solid supports and methods for oligomer synthesis
摘要
Methods and derivatized supports which are useful in solid-phase synthesis of peptides, oligonucleotides or other small organic molecules as well as arrays of ligands. The methods provide means to control the functional site density on a solid support. Some of the derivatized supports are polymer-coated or glycan-coated. Other methods for regenerating the surface of a used ligand array are also provided.
申请公布号
US5919523(A)
申请公布日期
1999.07.06
申请号
US19970956986
申请日期
1997.10.24
申请人
AFFYMETRIX, INC.
发明人
SUNDBERG, STEVEN A.;JACOBS, JEFFREY W.;SCHULLEK, JOHN R.;MCGALL, GLENN H.;MIRZABEKOV, ANDREI;TIMOFEEY, EDWARD;FUJIMOTO, DAVID;HOLMES, CHRISTOPHER P.;YANG, HUA