Secretion signal gene and expression vector containing it

摘要

PCT No. PCT/JP96/00198 Sec. 371 Date Oct. 2, 1996 Sec. 102(e) Date Oct. 2, 1996 PCT Filed Feb. 1, 1996 PCT Pub. No. WO96/23890 PCT Pub. Date Aug. 8, 1996A secretion signal gene having a base sequence encoding a polypeptide functional as a secretion signal in fission yeast Schizosaccharomyces pombe (hereinafter referred to as S. pombe), an expression vector having the gene and a foreign protein structural gene, a multicloning vector for construction of the expression vector which has the secretion signal gene, and efficient secretory production of the foreign protein structural gene product by S. pombe and the like.