发明名称 |
Mutant phosphoenolpyruvate carboxylase, its gene, and production method of amino acid |
摘要 |
A phosphoenolpyruvate carboxylase gene, which has mutation such as mutation to replace 625th glutamic acid from the N-terminus of phosphoenolpyruvate carboxylase with lysine, mutation to replace 438th arginine from the N-terminus with cysteine and the like, is introduced into Escherichia coli or coryneform bacteria, so as to produce a phosphoenolpyruvate carboxylase which is not substantially inhibited by aspartic acid, thereby amino acid is efficiently produced.
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申请公布号 |
US5919694(A) |
申请公布日期 |
1999.07.06 |
申请号 |
US19970967104 |
申请日期 |
1997.11.10 |
申请人 |
AJINOMOTO CO., INC. |
发明人 |
SUGIMOTO, MASAKAZU;SUZUKI, TOMOKO;MATSUI, HIROSHI;IZUI, KATSURA |
分类号 |
C12N9/88;C12P13/04;C12P13/06;C12P13/08;C12P13/14;C12P13/20;(IPC1-7):C07H21/04;C12N1/20 |
主分类号 |
C12N9/88 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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