发明名称 |
Halogenated naphthyl methoxy piperidines for mapping serotonin transporter sites |
摘要 |
Halogenated naphthyl methoxy piperidines having a strong affinity for the serotonin transporter are disclosed. Those compounds can be labeled with positron-emitting and/or gamma emitting halogen isotopes by a late step synthesis that maximizes the useable lifeterm of the label. The labeled compounds are useful for localizing serotonin transporter sites by positron emission tomography and/or single photon emission computed tomography.
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申请公布号 |
US5919797(A) |
申请公布日期 |
1999.07.06 |
申请号 |
US19970840651 |
申请日期 |
1997.04.24 |
申请人 |
EMORY UNIVERSITY |
发明人 |
GOODMAN, MARK M.;FARAJ, BAHJAT |
分类号 |
A61K51/04;C07B59/00;C07D211/46;(IPC1-7):C07D401/12;C07D215/00;A61K31/445 |
主分类号 |
A61K51/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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