发明名称 |
THE PROTEIN TYROSINE KINASE SUBSTRATE LAT AND ITS USE IN THE IDENTIFICATION OF (ANT)AGONISTS OF THE KINASE |
摘要 |
The invention generally relates to compositions and methods for identifying and testing tyrosine kinase signaling pathway agonists and antagonists, and more particularly, methods and compositions for screening compounds and identifying compounds that will modulate the interaction of protein tyrosine kinase substrates with their intracellular ligands, as well as between their intracellular ligands and other members of the signaling pathway.
|
申请公布号 |
CA2316769(A1) |
申请公布日期 |
1999.07.01 |
申请号 |
CA19982316769 |
申请日期 |
1998.12.23 |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SEC RETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
SAMELSON, LAWRENCE E.;ZHANG, WEIGUO |
分类号 |
C07K14/705;C07K14/725;C12N15/12;(IPC1-7):C12N15/12;C07K16/28;G01N33/50;G01N33/53;C12N15/62;C12Q1/68 |
主分类号 |
C07K14/705 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|