Oligonucleotides tagged with photoinducible redox-active unit

摘要

A nucleic acid oligomer with a photoinducible redox-active unit comprising one or more electron donors and one or more electron acceptors covalently attached is new. Also claimed is (1) a modified conductive surface comprising one or more modified nucleic acid oligomers as above bound to a conductive surface; and (2) a method for electrochemically detecting oligomer hybridisation, comprising contacting a modified conductive surface as above with nucleic acid oligomers.