METHOD OF PREPARING ENANTIOMERICALLY-ENRICHED TETRAHYDROBENZOTHIEPINE OXIDES

摘要

A process for preparing enantiomerically-enriched tetrahydrobenzothiepine oxides comprises cyclizing an enantiomerically-enriched aryl-3-propanalsulfoxide wherein the sulfur atom of the aryl-3-propanalsulfoxide is a chiral center.