发明名称 HUMAN SEL-10 POLYPEPTIDES AND POLYNUCLEOTIDES THAT ENCODE THEM
摘要 The present invention provides isolated nucleic acid molecules comprising a polynucleotide encoding either of two alternative splice variants of human sel10, one of which is expressed in hippocampal cells, and one of which is expressed in mammary cells. The invention also provides isolated sel-10 polypeptides and cell lines which express them in which A.beta. processing is altered.
申请公布号 CA2309391(A1) 申请公布日期 1999.07.01
申请号 CA19982309391 申请日期 1998.12.17
申请人 PHARMACIA & UPJOHN COMPANY 发明人 LI, JINHE;GURNEY, MARK E.;PAULEY, ADELE M.
分类号 C12N15/09;C07K14/47;C07K16/18;C12N5/02;C12N5/10;C12N15/12;C12Q1/68;(IPC1-7):C12N15/12;C12N15/62 主分类号 C12N15/09
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