PREVENTIVE AND/OR THERAPEUTIC AGENT FOR KIDNEY DISEASES
摘要
<p>A preventive and/or therapeutic agent for kidney diseases, containing as the active ingredient a tumor cytotoxic factor II (TCF-II) mutant which has undergone point mutation. The mutant is TCF-II wherein the Arg-Lys-Arg-Arg amino acid sequence beginning at the second position from the N-terminal is replaced by Ala-Ala-Ala-Ala or the Lys-Ile-Lys-Thr-Lys-Lys amino acid sequence beginning at the 27th position therefrom is replaced by Ala-Ile-Ala-Thr-Ala-Ala.</p>
申请公布号
EP0925791(A1)
申请公布日期
1999.06.30
申请号
EP19980909799
申请日期
1998.03.20
申请人
SNOW BRAND MILK PRODUCTS, CO., LTD.
发明人
KINOSAKI, MASAHIKO;OGAWA, HIROMI;MASUNAGA, HIROAKI;KOBAYASHI, FUMIE;YAMAGUCHI, KYOJI;HIGASHIO, KANJI