发明名称 |
Modulation of TH1/TH2 cytokine expression by ribavirin and ribavirin analogs in activated T-lymphocytes |
摘要 |
<p>Ribavirin is administered to a patient in a dosage range which is effective to modulate lymphokine expression in activated T cells. In particular, Ribavirin is used to suppress Th2-mediated T cell responses and promote Th1-mediated T cell response. In other aspects of the invention, one or more Ribavirin analogs are administered to a patient in a dosage range which is effective to modulate lymphokine expression in activated T cells. The Ribavirin analog(s) may be used to suppress or enhance Th1 or Th2-mediated T cell responses.</p> |
申请公布号 |
SI9720013(A) |
申请公布日期 |
1999.06.30 |
申请号 |
SI19970020013 |
申请日期 |
1997.01.21 |
申请人 |
ICN PHARMACEUTICALS, INC. |
发明人 |
TAM ROBERT;RAMASAMY KANDSAMY;AVERETT DEVRON |
分类号 |
A61K31/70;A61K31/7056;A61K38/21;A61K39/00;A61K45/06;C07H19/052;C07H19/056;C07H19/16;C07H19/24;(IPC1-7):A61K31/41 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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