| 发明名称 |
Production of a multimeric protein by cell fusion method |
| 摘要 |
The present invention features a method of producing a multimeric protein from a hybrid cell formed from the fusion of two or more cells, each of which cell is engineered to express one component of the multimeric protein, as well as a method for screening for successful fusion of the cells to produce a desired hybrid cell. The methods of the invention are widely applicable to the production of proteins having two or more components.
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| 申请公布号 |
US5916771(A) |
申请公布日期 |
1999.06.29 |
| 申请号 |
US19960730639 |
申请日期 |
1996.10.11 |
| 申请人 |
ABGENIX, INC.;JAPAN TOBACCO INC. |
发明人 |
HORI, NOBUAKI;DAVIS, CLAUDE GEOFFREY;ZSEBO, KRISZTINA M.;JAKOBOVITS, AYA |
| 分类号 |
C12N15/09;C07K14/00;C07K16/00;C07K16/24;C07K19/00;C12N5/16;C12N5/26;C12P21/00;C12P21/02;C12P21/04;C12P21/08;(IPC1-7):C12P21/04;C12N15/00;C12N5/06;C12N5/12 |
主分类号 |
C12N15/09 |
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