发明名称 |
Compounds and methods for the diagnosis and treatment of (b. microti) infection |
摘要 |
Compounds and methods for the diagnosis and treatment of Babesia microti infection are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of a B. microti antigen and DNA sequences encoding such polypeptides. Antigenic epitopes of such antigens are also provided, together with pharmaceutical compositions and vaccines comprising such polypeptides, DNA sequences or antigenic epitopes. Diagnostic kits containing such polypeptides, DNA sequences or antigenic epitopes and a suitable detection reagent may be used for the detection of B. microti infection in patients and biological samples. Antibodies directed against such polypeptides and antigenic epitopes are also provided. |
申请公布号 |
AU1820499(A) |
申请公布日期 |
1999.06.28 |
申请号 |
AU19990018204 |
申请日期 |
1998.12.11 |
申请人 |
CORIXA CORPORATION;MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH |
发明人 |
STEVEN G REED;MICHAEL J. LODES;RAYMOND HOUGHTON;PAUL R SLEATH;DAVID PERSING;ELIZABETH BRUINSMA |
分类号 |
A61K38/00;A61K39/00;C07K14/44;C12N1/21;C12N15/30;C12P21/04 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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