| 摘要 |
Phenyl-oxazolidinone cpds. of the formula (I) and their salts are new. Q = pyrrol-1-yl, pyrazol-1-yl, imidazol-1-yl, 1,3,4-triazol-1-yl, 1H-1,2,4-triazol-1-yl, 1H-1,2,3-triazol-1-yl, 1H-1,2,3-triazol-2-yl, 1,2,3,4-tetrazol-2-yl or 1,2,3,4-tetrazol-1-yl (all substd. by R3), or indol-1-yl, benzimidazol-1-yl, 1H-indazol-1-yl, indazol-2-yl, or 1H-pyrrolo[2,3-b]pyridin-1-yl (all being substd. by R3 in both rings) or 1H-benzotriazol-1-yl, 1H-benzotriazol-2-yl or 1H-1,2,3-triazolo[4,5-b]-pyridine-1-yl or 1H-1,2,3-triazolo[4,5-b]-pyridine-2-yl (all being substd. by R3 in the 6-membered ring only); R1 = H, OCH3, F or Cl; R2 is H, 1-8C alkyl (opt. substd. by one of more F. Cl, OH, 1-8C alkoxy or 1-8C aryloxy), 3-6C cycloalkyl, NH2, mono-or di-(1-8C) alkylamino or 1-8C alkoxy; R3 = H, F, Cl, Br, OR4 SR4, S(O)nR4, CN, O2CR4, NHCOR4, NHCO2R4; NHSO2R4, CO2R4, CON(R4)2, COR4 or 1-8C alkyl or 3-8C cycloalkyl (opt. substd. by one or more of the preceding R3 gps.) or phenyl (opt. substd. by one or more of the preceeding R3 gps.); n = 1 or 2; R4 = H, 1-6C alkyl or 3-8C cycloalkyl. (opt. substd. by one or more of Cl, F, OH, 1-4C alkoxy, 1-4C acyl, 1-4C acyloxy or O2CCH2N(CH3)2 or phenyl (opt. substd. by one or more F, Cl, 1-4 alkyl, OH, 1-4C alkoxy, 1-4C acyl, 1-4C acyloxy or O2CCH2N(CH3)2. |
