beta (1-3)-GLUCAN DIAGNOSTIC ASSAYS

摘要

Methods of isolating beta (1-3)-glucan or beta (1-3)-glucan-containing organisms in a sample, or of detecting the presence of beta (1-3)-glucan or beta (1-3)-glucan-containing organisms in a sample, utilizing binding agents for beta (1-3)-glucan, such as LacCer, GalCer, globotriaosylceramide and asialoganglioside-GM1, are described. Methods of diagnosing fungal infection, by detecting beta (1-3)-glucan or beta (1-3)-glucan-containing organisms, are also described. Antibodies and kits useful in the methods are also disclosed.