| 发明名称 |
C-TERMINAL REGION OF AGOUTI-RELATED TRANSCRIPT (ART) PROTEIN |
| 摘要 |
Novel polypeptides derived from the C-terminal region of the human and mouse agouti related transcript (ART) proteins are provided. Also provided are DNA sequences encoding the novel C-terminal polypeptides. The novel C-terminal polypeptides can be used to inhibit the binding of melanocyte stimulating hormones to melanocortin receptors. Methods of identifying inhibitors of the binding of ART protein to melanocortin receptors are also provided.
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| 申请公布号 |
CA2314971(A1) |
申请公布日期 |
1999.06.24 |
| 申请号 |
CA19982314971 |
申请日期 |
1998.12.11 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
TOTA, MICHAEL R.;VAN DER PLOEG, LEONARDUS H.T.;FONG, TUNG MING |
| 分类号 |
G01N33/50;C07K14/435;C07K14/47;C07K19/00;C12N15/09;C12Q1/00;G01N33/15;G01N33/53;G01N33/566;(IPC1-7):G01N33/53;C12N15/12 |
主分类号 |
G01N33/50 |
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