| 摘要 |
<p>The invention is directed to a non-hygroscopic stable crystalline form of the antithrombotic compound N-[N-[N-(4-piperdin-4-yl)butanoyl)-N-ethylglycyl]-(L)-aspartyl]-(L)- beta -cyclohexyl-alanine amide, to processes for preparing said stable crystalline form, to a pharmaceutical composition thereof, and intermediates thereof, and the invention is directed also to processes for preparing a compound of the formula wherein: A, B, Z, E1, E2, G, R, m, n, and p are as defined herein.</p> |
| 申请人 |
AVENTIS PHARMACEUTICALS INC. |
发明人 |
CHRZAN, ZOFIA, J.;MENCEL, JAMES, J.;TOLEDO-VELASQUEZ, DAVID;WINDISCH, VINCENT;WOODWARD, RICK, G.;SALAZAR, DIANE, C.;VEMURI, NARASIMHA, M.;GARDETTO, ANTHONY, J.;POWERS, MATTHEW, R.;KUBIAK, GREGORY, G.;LIU, ROBERT, C.;VANASSE, BENOIT, J.;SHERBINE, JAMES, P.;RODRIGUEZ, WALTER;SLEDESKI, ADAM, W. |
