| 发明名称 |
Methods and means for inducing apoptosis by interference in RNA processing |
| 摘要 |
<p>The invention relates to activation of apoptosis by means of interference with the function of snRNPs and hnRNP-like compounds. Also the invention relates to anti-tumor therapies with compounds, which negatively interfere with snRNPs and hnRNP-like compounds leading to induction of apoptosis, resulting in the elimination of tumor cells. Also the invention relates to therapies for diseases related to aberrant apoptosis induction, such as auto-immune diseases.</p> |
| 申请公布号 |
EP0924296(A2) |
申请公布日期 |
1999.06.23 |
| 申请号 |
EP19980204089 |
申请日期 |
1998.12.03 |
| 申请人 |
LEADD B.V. |
发明人 |
NOTEBORN, MATHIEU HUBERTUS MARIA;DANEN-VAN OORSCHOT, ASTRID ADRIANA ANNA MARIA |
| 分类号 |
A61K38/00;C07K14/47;C12N1/21;C12N15/12;(IPC1-7):C12N15/12;C12N1/19;A61K38/17;C12Q1/68 |
主分类号 |
A61K38/00 |
| 代理机构 |
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代理人 |
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